When you enter a bank opening balance in QuickFile it will need to make a balancing entry on the ledgers to explain what that balance is derived from.
As a temporary measure we will put the balancing entry into Suspense, just so you can get on with things. Later then you need to journal that balance out of suspense into the appropriate ledgers. How you do this is a little bit more complex, especially if you are coming from Excel, as this is not a double entry accounting system.
So what you would need to do here is figure out how much of that balance is derived from sales, loans, expenses etc then journal the suspense balance over to these ledgers accordingly.
I would definitely have a chat with a bookkeeper here as they will most likely be able to get all your opening balances set and save you a bit of time.